Manufacturer: Sanofi Aventis
Substance: Insulin Glulisine (rDNA origin)
Pack: 1 box (5 x 3 mL pens 100 U/mL)
Apidra SoloStar (Insuline Glulisine)
Apidra SoloStar (Insuline Glulisine) is a biosynthetic rapid-acting insulin analogue with a little difference from human insluin, that is used for adults and childrens with diabetes mellitus to control the high blood sugar. For the first time, insulin glulisine was developed by Sanofi-Aventis and it is sold under the trade name "APIDRA". Insulin is used for treating the hyperglycemia caused by Type1 and Type2 Diabets. APIDRA comes in form of steril, clear colorless solution for subcutaneous or intravenous injection. Apidra SoloStar by Sanofi-Aventis is designed to facilitate the administration for users, so it comes in form of prefilled insulin pen. Each milliliter of APIDRA contains 100 UNITS that is formed from: 3.49mg - insuline glulisine, 3.15mg - metacresol, 6mg - tromethamine, 5mg - sodium chloride, 0.01mg - polysorbate 20 and injection water. One unit of APIDRA has the same glucose-lowering effect as one unit of regular human insulin when it is given intravenously. In case of subcutaneously administration, APIDRA is more rapid in action, but has a shorter time of action than regular human insulin.The dosage of Apidra administration should be individualized, every daily requirement varies between 0.5 to 1 Unit/kg/day. That's why until administration is better to consult a doctor.
Apidra SoloStar can be administrated like:
- Subcutaneous Administration
APIDRA should be administrating within 15 minutes before the meal or within 20 minutes after strating the meal. A subcutaneous injection of APIDRA is generally used in regimes of intermediate or long-acting insulin. APIDRA si recommended to be injected subcutaneously in the abdominal wall, thigh or upper arm. To reduce the risk of lipodistrofy, the injections sites should be rotated between the same regions (abdomen, thigh or upper arm).
- Continuous Subcutaneous Infusion (Insulin Pump)
APIDRA can be administrated by Continuous Subcutaneous Infusion in the abdominal wall, but it's prohibited to use diluted or mixed insulins in external pumps. The external infusion pumps must be based on the total daily insulin dose from the previous regim. Also it's recommended to rotate the injections between the same regions to avoid the risk of lipodistrofy. Before using an isulin pump with APIDRA, read the pump label and instructions.
- Intravenous Administration
APIDRA can be administrated intrevanously for extreme hyperglycemia, but must be performed under the supervision of a medical professional with close monitoring to avoid hypokalemia or hypoglycemia. APIDRA for intrevaneously using comes in polyvinyl chloride bags with concentration of 0.05 Units/ml - 1Unit/ML insulin glulisine (infusion system). It is prohibited to administrate intravenously the insulin mixtures.
Apidra SoloStar can cause seriously side effects that can lead to death. Some effects caused are:
- Hypoglycemia (low blood sugar), symptoms being dizziness, confusion, sweating, headache, slurred speech, fast heartbeat, anxiety, hunger, irritability, mood changes.
- Hypokalemia (low potassium in blood).
- Heart failure.
- Serious allergic reactions, symptoms being shortness of breath, trouble breathing, fast pulse, rash over whole body.
The most common side effects of APIDRA include: hypoglycemia, rash, itching, weight gain, swelling, allergic reaction, lipodistrophy.
Do NOT share needles, insulin pens or syringes with others even if the needle is changed.
Do NOT reuse needles. You may give other people a serious infection or get a serious infection from them.
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